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The power of an immunotherapy can be added to COTELLIC + ZELBORAF9
Learn more about this combination and appropriate patients >
Models are not real patients.
Take COTELLIC one time a day for 21 days, followed by 7 days off treatment, to complete a 28-day treatment cycle.
Pills are not actual size.
Take ZELBORAF every 12 hours for every day in the 28-day cycle (no rest period).
Pills are not actual size.
Dose changes
Get a dosing calendar to help you keep track of treatment
Get a dosing calendar to help you keep track of treatment
Your cancer medicines are important to your health. Take your medicines exactly as your healthcare provider tells you. Do not change your dose or stop taking your medicines unless your healthcare provider tells you to.
Routines, visual reminders, and simple tools may help you remember to take your medicines.
Get a dosing calendar to help you keep track of treatment
IMPORTANT: If your healthcare provider prescribes ZELBORAF (vemurafenib), also read the Medication Guide that comes with ZELBORAF.
What is COTELLIC?
COTELLIC is a prescription medicine that is used with the medicine ZELBORAF, to treat a type of skin cancer called melanoma:
Your healthcare provider will perform a test to make sure that COTELLIC is right for you.
It is not known if COTELLIC is safe and effective in children under 18 years of age.
Before you take COTELLIC and ZELBORAF, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain medicines may affect the blood levels of COTELLIC.
Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
How should I take COTELLIC and ZELBORAF in combination?
What should I avoid during treatment with COTELLIC and ZELBORAF?
Avoid sunlight during treatment with COTELLIC and ZELBORAF. COTELLIC and ZELBORAF can make your skin sensitive to sunlight. You may burn more easily and get severe sunburns. To help protect against sunburn:
COTELLIC and ZELBORAF may cause serious side effects, including:
Your healthcare provider should check your skin before you start taking COTELLIC and ZELBORAF, and every 2 months during treatment with COTELLIC and ZELBORAF. Your healthcare provider may continue to check your skin for 6 months after you stop taking COTELLIC and ZELBORAF.
See “What should I avoid during treatment with COTELLIC and ZELBORAF?” for information on protecting your skin during treatment with COTELLIC and ZELBORAF.
The most common side effects of COTELLIC in combination with ZELBORAF include:
Your healthcare provider will take blood tests during treatment with COTELLIC in combination with ZELBORAF. The most common changes to blood tests include:
These are not all the possible side effects of COTELLIC and ZELBORAF.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Genentech at (888)-835-2555.
Please see both Full COTELLIC Prescribing Information and Patient Information and Full ZELBORAF Prescribing Information and Medication Guide for additional Important Safety Information.
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