Financial Assistance Options

No matter what type of health insurance you have, and even if you have none at all, there may be some potential options available to help you afford your medicine.

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Use our financial assistance tool to see which programs may be right for you. If you would rather talk through some potential options, call us at 888-249-4918 (6AM-5PM PST, Monday through Friday).


If you have insurance coverage and need help affording COTELLIC, these programs may help:

Genentech Oncology Co-pay Assistance Program

Co-pay Card Assistance

With the Genentech Oncology Co-pay Assistance Program, eligible patients with commercial insurance could pay as little as $5 per treatment for COTELLIC. Co-pay assistance of up to $25,000 is provided per calendar year.

You may be eligible if you:

  • Are taking COTELLIC for an FDA-approved use
  • Are 18 years of age or older or have a Legally Authorized Person over the age of 18 to manage the program
  • Have commercial (private or non-governmental) insurance. This includes plans available through state and federal health insurance exchanges
  • Live and receive treatment in the United States or U.S. Territories
  • Are not receiving assistance through the Genentech Patient Foundation or any other charitable organization for the same expenses covered by the program
  • Do not use a state or federal healthcare plan to pay for your medication. This includes, but is not limited to, Medicare, Medicaid and TRICARE

The Co-pay Program is valid ONLY for patients with commercial (private or non-governmental) insurance who have a valid prescription for a Food and Drug Administration (FDA)-approved indication of a Genentech medicine. Patients using Medicare, Medicaid or any other federal or state government program (collectively, “Government Programs”) to pay for their Genentech medicine are not eligible.

Under the Program, the patient may pay a co-pay. The final amount owed by a patient may be as little as $0 for the Genentech medicine (see Program specific details). The total patient out-of-pocket cost is dependent on the patient’s health insurance plan. The Program assists with the cost of the Genentech medicine only. It does not assist with the cost of other medicines, procedures or office visit fees. After reaching the maximum annual Program benefit amount, the patient will be responsible for all remaining out-of-pocket expenses. The Program benefit amount cannot exceed the patient’s out-of-pocket expenses for the cost associated with the Genentech medicine.

All participants are responsible for reporting the receipt of all Program benefits as required by any insurer or by law. The Program is only valid in the United States and U.S. Territories, is void where prohibited by law and shall follow state restrictions in relation to AB-rated generic equivalents (e.g., MA, CA) where applicable. No party may seek reimbursement for all or any part of the benefit received through the Program. The Program is intended for the patient. Only the patient using the Program may receive the funds made available through the Program. The Program is not intended for third parties who reduce the amount available to the patient or take a portion for their own purposes. Patients with health plans that redirect Genentech Program assistance intended for patient out- of-pocket costs may be subject to alternate Program benefit structures. Genentech reserves the right to rescind, revoke or amend the Program without notice at any time.

Additional terms and conditions apply. Please visit the Co-pay Program website for the full list of Terms and Conditions.

View full TERMS AND CONDITIONS.

Apply for the Genentech Oncology Co-pay Assistance Program

  • Commercial insurance: An insurance plan you get from a private health insurance company. This can be insurance from your job, from a plan you bought yourself or from a Health Insurance Marketplace (for example, from HealthCare.gov). Medicare and Medicaid are not considered commercial insurance. 

Independent Co-pay Assistance Foundations

Independent Co-pay Assistance

An independent co-pay assistance foundation is a charitable organization providing financial assistance to patients with specific disease states, regardless of treatment. Patients who are commercially or publicly insured, including those covered by Medicare and Medicaid, can contact the foundations directly to request assistance. Eligibility requirements, all aspects of the application process, turnaround times and the type or amount of assistance available (if any) can vary by foundation. 

These foundations may be able to help. Please check their websites for up-to-date information.

These organizations are independent of Genentech and may require you to provide personal or financial information directly to the organization to enroll in their respective programs. Genentech cannot share any information you have provided to us.

Independent co-pay assistance foundations have their own rules for eligibility. We have no involvement or influence in independent foundation decision-making or eligibility criteria and do not know if a foundation will be able to help you. We can only refer you to a foundation that supports your disease state. This information is provided as a resource for you. We do not endorse or show preference for any particular foundation. The foundations in this list may not be the only ones that might be able to help you.


If you have financial difficulty or do not have insurance coverage and need help affording COTELLIC, this program may help:

Genentech Patient Foundation

Genentech Patient Foundation

The Genentech Patient Foundation gives free COTELLIC to people who have been prescribed this medicine and don’t have insurance or that have financial concerns and meet certain eligibility criteria.

You may be eligible if your insurance coverage and income match one of these situations:

  • Uninsured patients with incomes under $150,000
  • Insured patients without coverage for COTELLIC with incomes under $150,000
  • Insured patients with coverage for a Genentech medicine:
    • With unaffordable out-of-pocket costs
    • Who have pursued other forms of financial assistance
    • With household size and income within certain guidelines

Enrollment Process for the Genentech Patient Foundation

If you meet the criteria and would like to enroll:

  1. Complete the Patient Consent Form, which is available in English and Spanish, below: 
  2. Once you have completed the Patient Consent Form, please let your doctor's office know that you are applying for assistance with the Genentech Patient Foundation. Your doctor will have to complete another form called the Prescriber Foundation Form. Both forms are required. We must have both the Patient Consent Form and the Prescriber Foundation Form before we can help you.

What to expect next:

  • The request will be processed within five business days upon receipt of both required forms.
  • You and your provider will be contacted to discuss the application outcome and any next steps.

If you have any questions about the criteria, please contact a Foundation Specialist at 888-941-3331 (Mon.–Fri., 6AM–5PM PST).

Genentech reserves the right to modify or discontinue the program at any time and to verify the accuracy of information submitted.


Not sure which programs may be able to help you? We'll walk you through some potential options with the financial assistance tool.

  • Commercial insurance: An insurance plan you get from a private health insurance company. This can be insurance from your job, from a plan you bought yourself or from a Health Insurance Marketplace (for example, from HealthCare.gov). Medicare and Medicaid are not considered commercial insurance. 

  • Public insurance: A health insurance plan you get from the federal or state government. This includes Medicare, Medicaid, TRICARE and DoD/VA insurance.

  • For example, a household size of 1 with income of less than $75,000 may meet the criteria for assistance. Add $25,000 for each additional person in the household. There is no maximum number of people you may add.

Important Safety Information & Indication

Important: If your healthcare provider prescribes ZELBORAF (vemurafenib), also read the Medication Guide that comes with ZELBORAF.

What is COTELLIC?

COTELLIC is a prescription medicine that is used in combination with the medicine ZELBORAF, to treat adults with a type of skin cancer called melanoma:

  • that has spread to other parts of the body (metastatic) or cannot be removed by surgery (unresectable), and
  • that has a certain type of abnormal “BRAF” gene

Your healthcare provider will perform a test to make sure that COTELLIC is right for you. It is not known if COTELLIC is safe and effective in children under 18 years of age.

Before you take COTELLIC and ZELBORAF, tell your healthcare provider about all of your medical conditions, including if you:

  • have skin problems or history of skin problems, other than skin cancer (melanoma)
  • have bleeding problems or have any medical conditions or take any medicines that increase your risk of bleeding
  • have heart problems, including a condition called long QT syndrome
  • have eye problems
  • have liver or kidney problems
  • have muscle problems
  • have had or are planning to receive radiation therapy
  • have been told that you have low blood levels of potassium, calcium, or magnesium
  • are pregnant or plan to become pregnant. COTELLIC and ZELBORAF can harm your unborn baby
    • Females who are able to become pregnant should use effective birth control (contraception) during treatment with COTELLIC and ZELBORAF, and for 2 weeks after the final dose of COTELLIC or ZELBORAF (whichever is taken later).
    • Talk to your healthcare provider about birth control methods that may be right for you.
    • Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment with COTELLIC and ZELBORAF.
  • are breastfeeding or plan to breastfeed. It is not known if COTELLIC or ZELBORAF passes into your breast milk. Do not breastfeed during treatment with COTELLIC and ZELBORAF and for 2 weeks after the final dose of COTELLIC or ZELBORAF (whichever is taken later). Talk to your healthcare provider about the best way to feed your baby during this time.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain medicines may affect the blood levels of COTELLIC.

Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

How should I take COTELLIC and ZELBORAF in combination?

  • Take COTELLIC and ZELBORAF exactly as your healthcare provider tells you. Do not change your dose or stop taking COTELLIC and ZELBORAF unless your healthcare provider tells you to.
  • Take COTELLIC one time a day for 21 days, followed by 7 days off treatment, to complete a 28-day treatment cycle.
  • Take ZELBORAF every 12 hours for every day in the 28-day cycle (no rest period).
  • Do not crush or chew ZELBORAF tablets.
  • Take COTELLIC and ZELBORAF with or without food.
  • If you vomit after taking your dose of COTELLIC or ZELBORAF, do not take an additional dose. Take your next dose as scheduled.
  • If you miss a dose of COTELLIC, take your next dose as scheduled.
  • If you miss a dose of ZELBORAF, take it as soon as you remember. If it is within 4 hours of your next scheduled dose, just take your next dose at your regular time. Do not make up for the missed dose.
  • If you take too much ZELBORAF, call your healthcare provider or go the nearest hospital emergency room right away.

What should I avoid during treatment with COTELLIC and ZELBORAF?

Avoid sunlight during treatment with COTELLIC and ZELBORAF. COTELLIC and ZELBORAF can make your skin sensitive to sunlight. You may burn more easily and get severe sunburns. To help protect against sunburn:

  • When you go outside, wear clothes that protect your skin, including your head, face, hands, arms, and legs.
  • Use lip balm and a broad-spectrum sunscreen with SPF 30 or higher.

What are the possible side effects of COTELLIC and ZELBORAF?

COTELLIC and ZELBORAF may cause serious side effects, including:

  • Risk of new skin cancers. COTELLIC in combination with ZELBORAF may cause new skin cancers (cutaneous squamous cell carcinoma, keratoacanthoma, or basal cell carcinoma). New melanoma lesions have occurred in people who take ZELBORAF.

Check your skin regularly and tell your healthcare provider right away if you have any skin changes including:

  • new wart
  • skin sore or reddish bump that bleeds or does not heal
  • change in size or color of a mole

Your healthcare provider should check your skin before you start taking COTELLIC and ZELBORAF, and every 2 months during treatment with COTELLIC and ZELBORAF. Your healthcare provider may continue to check your skin for 6 months after you stop taking COTELLIC and ZELBORAF.

  • Risk of other cancers. ZELBORAF may also cause another type of cancer called non-cutaneous squamous cell carcinoma (non-cuSCC). Talk with your healthcare provider about your risk for these cancers.

Your healthcare provider should also check for cancers that may not occur on the skin. Tell your healthcare provider about any new symptoms that develop during treatment with COTELLIC and ZELBORAF.

  • Bleeding problems. COTELLIC can cause serious bleeding problems. Call your healthcare provider and get medical attention right away if you get any signs of bleeding, including:
    • red or black stools (looks like tar)
    • blood in your urine
    • headaches
    • cough up or vomit blood
    • stomach (abdominal) pain
    • unusual vaginal bleeding
    • dizziness or weakness
  • Heart problems. Your healthcare provider should do tests before and during treatment to check your heart function. Tell your healthcare provider if you get any of these signs or symptoms of heart problems:
    • persistent coughing or wheezing
    • shortness of breath
    • swelling of your ankles and feet
    • tiredness
    • increased heart rate
  • Allergic reactions can happen while taking ZELBORAF, and can be severe. Stop taking ZELBORAF and get medical help right away if you get any of these symptoms of an allergic reaction:
    • rash or redness all over your body
    • trouble breathing or swallowing
    • throat tightness or hoarseness
    • feel faint
    • fast heartbeat
  • Severe rash and other severe skin reactions. Tell your healthcare provider right away if you get any of these symptoms:
    • a rash that covers a large area of your body
    • blisters
    • peeling skin

Stop taking ZELBORAF and call your doctor right away if you get a skin rash with any of the following symptoms, because you may have a severe skin reaction: 

  • blisters on your skin
  • blisters or sores in your mouth
  • peeling of your skin
  • fever
  • redness or swelling of your face, hands, or soles of your feet

  • Eye problems. Tell your healthcare provider right away if you get any of these symptoms:
    • blurred vision
    • partly missing vision or loss of vision
    • see halos
    • eye pain, swelling, or redness
    • any other vision changes

Your healthcare provider should check your eyes if you notice any of the symptoms above.

  • Changes in the electrical activity of your heart called QT prolongation. QT prolongation can cause irregular heartbeats that can be life threatening. Your doctor should do tests before you start taking ZELBORAF and during your treatment with ZELBORAF to check the electrical activity of your heart and your body salts (electrolytes). Tell your doctor right away if you feel faint, lightheaded, dizzy, or feel your heart beating irregularly or fast while taking ZELBORAF. These may be symptoms related to QT prolongation.
  • Liver problems or liver injury. Your healthcare provider should do blood tests to check your liver function before and during treatment. Tell your healthcare provider right away if you get any of these symptoms:
    • yellowing of your skin or the white of your eyes
    • dark or brown (tea color) urine
    • nausea or vomiting
    • feeling tired or weak
    • loss of appetite
    • pain in the right side of your stomach
  • Muscle problems (rhabdomyolysis). COTELLIC can cause muscle problems that can be severe. Treatment with COTELLIC may increase the level of an enzyme in your blood called creatine phosphokinase (CPK) and may be a sign of muscle damage. Your healthcare provider should do a blood test to check your levels of CPK before and during treatment. Tell your healthcare provider right away if you get any of these symptoms:
    • muscle aches or pain
    • muscle spasms and weakness
    • dark, reddish urine
  • Skin sensitivity to sunlight (photosensitivity). Skin sensitivity to sunlight during treatment with COTELLIC and ZELBORAF is common and can sometimes be severe. Tell your healthcare provider if you get any of these symptoms:
    • red, painful, itchy skin that is hot to touch
    • sun rash
    • skin irritation
    • bumps or tiny papules
    • thickened, dry, wrinkled skin
  • Worsening side effects from radiation treatment that can sometimes be severe or lead to death. Tell your healthcare provider if you have had or are planning to receive radiation therapy.
  • Kidney injury. Your healthcare provider should do blood tests to check your kidney function before you start taking ZELBORAF and during treatment.
  • Connective tissue disorders. Tell your healthcare provider if you develop an unusual thickening of the palms of your hands along with tightening of the fingers inward or any unusual thickening of the soles of your feet which may be painful.

See “What should I avoid during treatment with COTELLIC and ZELBORAF?” for information on protecting your skin during treatment with COTELLIC and ZELBORAF.

The most common side effects of COTELLIC in combination with ZELBORAF include:

  • diarrhea
  • vomiting
  • nausea
  • fever
  • sunburn or sun sensitivity

Your healthcare provider will take blood tests during treatment with COTELLIC in combination with ZELBORAF. The most common changes to blood tests include:

  • increased blood levels of liver enzymes (GGT, ALT, or AST)
  • increased blood level of enzyme from muscle (creatine phosphokinase)
  • decreased blood level of phosphate, sodium or potassium
  • increased blood level of liver or bone enzyme (alkaline phosphatase)
  • decreased blood level of a type of white blood cell (lymphocyte)

COTELLIC may cause fertility problems in males and females, which may affect your ability to have a child. Talk to your healthcare provider if this is a concern for you.

These are not all of the possible side effects of COTELLIC and ZELBORAF. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Genentech at (888)-835-2555.

Please see both Full COTELLIC Prescribing Information and Patient Information and Full ZELBORAF Prescribing Information and Medication Guide for additional Important Safety Information.

    • TECENTRIQ Prescribing Information. Genentech, Inc. 2022.

      TECENTRIQ Prescribing Information. Genentech, Inc. 2022.